| Rank | Name | Tm/Bye | Age | G | Cmp | Att | Cm% | PYd | Y/Att | PTD | Int | Rsh | Yd | TD | FantPt |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Tom Brady | TB/11 | 45 | 16.7 | 454.2 | 681.6 | 66.6 | 5082 | 7.46 | 38.5 | 12.7 | 27.0 | 53 | 1.8 | 411.50 |
| 2 | Patrick Mahomes II | KC/8 | 27 | 16.7 | 419.6 | 643.2 | 65.2 | 4819 | 7.49 | 34.6 | 11.8 | 63.7 | 350 | 2.6 | 418.15 |
| 3 | Justin Herbert | LAC/8 | 24 | 16.7 | 424.0 | 635.9 | 66.7 | 4784 | 7.52 | 36.3 | 13.7 | 64.7 | 309 | 3.3 | 421.40 |
| 4 | Josh Allen | BUF/7 | 26 | 16.7 | 412.4 | 634.6 | 65.0 | 4620 | 7.28 | 35.5 | 13.6 | 110.6 | 625 | 6.3 | 459.70 |
| 5 | Dak Prescott | DAL/9 | 29 | 16.5 | 410.9 | 613.2 | 67.0 | 4641 | 7.57 | 32.3 | 11.0 | 51.4 | 207 | 2.8 | 387.75 |