| Rank | Name | Tm/Bye | Age | G | Cmp | Att | Cm% | PYd | Y/Att | PTD | Int | Rsh | Yd | TD | FantPt |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Tom Brady | TB/11 | 45 | 17.0 | 440.0 | 660.0 | 66.7 | 4950 | 7.50 | 41.0 | 12.0 | 25.0 | 75 | 2.0 | 419.00 |
| 2 | Patrick Mahomes II | KC/8 | 27 | 17.0 | 420.0 | 640.0 | 65.6 | 4950 | 7.73 | 38.0 | 12.0 | 60.0 | 360 | 3.0 | 441.50 |
| 3 | Derek Carr | LV/6 | 31 | 17.0 | 412.0 | 600.0 | 68.7 | 4550 | 7.58 | 28.0 | 13.0 | 34.0 | 120 | 1.0 | 344.50 |
| 4 | Justin Herbert | LAC/8 | 24 | 17.0 | 410.0 | 620.0 | 66.1 | 4640 | 7.48 | 35.0 | 14.0 | 55.0 | 290 | 3.0 | 405.00 |
| 5 | Dak Prescott | DAL/9 | 29 | 17.0 | 407.0 | 590.0 | 69.0 | 4600 | 7.80 | 34.0 | 10.0 | 50.0 | 170 | 4.0 | 397.00 |