| Player | TM | Wk13 | Wk14 | Wk15 | Wk16 | Wk17 | Wk18 | Wk19 | Targ | T/TmG | T/G | REC | YD | Y/R | TD | Rec% |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Christian McCaffrey | SF | 10 | 7 | 11 | 13 | 1 | - | - | 124 | 7.8 | 7.8 | 107 | 867 | 8.1 | 6 | 86.3 |
| George Kittle | SF | 9 | 9 | 8 | 12 | 14 | - | - | 135 | 8.4 | 8.4 | 88 | 1377 | 15.6 | 5 | 65.2 |
| Chris Conley | SF | 7 | 3 | 3 | 5 | 3 | - | - | 54 | 3.4 | 3.2 | 32 | 334 | 10.4 | 5 | 59.3 |
| Kyle Juszczyk | SF | 3 | 3 | 1 | 0 | 2 | - | - | 40 | 2.5 | 2.5 | 30 | 324 | 10.8 | 1 | 75.0 |
| Trent Taylor | SF | 1 | 2 | 2 | 2 | 4 | - | - | 40 | 2.5 | 2.9 | 26 | 215 | 8.3 | 1 | 65.0 |