Weekly Injury Report By Team: Week 17 2025
The Probable designation is not officially reported by the NFL, but used on this report for players who go from a game-time decision to active, or players who go from missing (or limited) practice to completing a full practice later in the week.
| Player | Position | Status | Issue/Injury | |
|---|---|---|---|---|
| Dallas Cowboys @ WAS, Thursday, 1:00PM ET | ||||
| Phil Mafah | RB | Questionable | Shoulder | |
| Miles Sanders | RB | Out | Knee/ankle | |
| Javonte Williams | RB | Questionable | Neck | |
| Ryan Flournoy | WR | Questionable | Knee | |
| KaVontae Turpin | WR | Questionable | Shoulder | |
| Quinnen Williams | DT | Questionable | Neck | |
| Payton Turner | DE | Questionable | Ribs | |
| DeMarvion Overshown | LB | Questionable | Concussion | |
| Jack Sanborn | LB | Out | Groin | |
| Juanyeh Thomas | S | Out | Migraine | |
| Donovan Wilson | S | Questionable | Hip | |
| DaRon Bland | CB | Out | Foot | |
| Josh Butler | CB | Questionable | Knee | |
| Caelen Carson | CB | Questionable | Hamstring | |
| Shavon Revel Jr. | CB | Probable | Knee | |
| Washington Commanders v DAL, Thursday, 1:00PM ET | ||||
| Jayden Daniels | QB | Out | Left Elbow | |
| Marcus Mariota | QB | Questionable | Right Hand/quad | |
| Austin Ekeler | RB | Out | Achilles | |
| Colson Yankoff | RB | Probable | Ankle | |
| Ja'Corey Brooks | WR | Out | Undisclosed | |
| Noah Brown | WR | Out | Ribs | |
| Jaylin Lane | WR | Out | Ankle | |
| Luke McCaffrey | WR | Out | Shoulder | |
| Zach Ertz | TE | Out | Knee | |
| Tyree Jackson | TE | Out | Undisclosed | |
| Eddie Goldman | DT | Out | Concussion | |
| Daron Payne | DT | Questionable | Back | |
| Dorance Armstrong | DE | Out | Knee | |
| Javontae Jean-Baptiste | DE | Out | Pectoral | |
| Deatrich Wise Jr | DE | Out | Quad | |
| Nick Bellore | LB | Questionable | Concussion | |
| Bobby Wagner | LB | Questionable | Knee/rest | |
| Trey Amos | CB | Out | Fibula | |
| Marshon Lattimore | CB | Out | Knee | |
| Darius Rush | CB | Out | Groin | |
| Detroit Lions @ MIN, Thursday, 4:30PM ET | ||||
| Kye Robichaux | RB | Out | Undisclosed | |
| Tom Kennedy | WR | Questionable | Abdomen | |
| Amon-Ra St. Brown | WR | Questionable | Knee | |
| Sam LaPorta | TE | Out | Back | |
| Brock Wright | TE | Out | Neck | |
| Alim McNeill | DT | Questionable | Abdomen | |
| Levi Onwuzurike | DT | Out | Knee (acl) | |
| Marcus Davenport | DE | Questionable | Shoulder | |
| Al-Quadin Muhammad | DE | Questionable | Knee | |
| Josh Paschal | DE | Out | Shoulder | |
| Zach Cunningham | LB | Out | Hamstring | |
| Ezekiel Turner | LB | Out | Achilles | |
| Brian Branch | S | Out | Achillies | |
| Dan Jackson | S | Out | Leg | |
| Kerby Joseph | S | Out | Knee | |
| Terrion Arnold | CB | Out | Shoulder | |
| Avonte Maddox | CB | Questionable | Back | |
| Ennis Rakestraw Jr. | CB | Out | Shoulder | |
| Amik Robertson | CB | Questionable | Hand | |
| Minnesota Vikings v DET, Thursday, 4:30PM ET | ||||
| J.J. McCarthy | QB | Out | Hand | |
| Carson Wentz | QB | Out | Shoulder | |
| Ty Chandler | RB | Questionable | Knee | |
| Aaron Jones Sr. | RB | Questionable | Ankle | |
| Jordan Mason | RB | Questionable | Ankle | |
| Rondale Moore | WR | Out | Knee | |
| Gavin Bartholomew | TE | Questionable | Lower Back | |
| T.J. Hockenson | TE | Questionable | Shoulder | |
| Javon Hargrave | DT | Questionable | Thigh | |
| Jonathan Greenard | DE | Out | Shoulder | |
| Austin Keys | LB | Probable | Ankle | |
| Eric Wilson | LB | Questionable | Thumb | |
| Joshua Metellus | S | Out | Shoulder | |
| Jeff Okudah | CB | Out | Concussion | |
| Denver Broncos @ KC, Thursday, 8:15PM ET | ||||
| Michael Burton | RB | Out | Hamstring | |
| J.K. Dobbins | RB | Out | Foot | |
| Pat Bryant | WR | Questionable | Concussion | |
| Nate Adkins | TE | Questionable | Knee | |
| Lucas Krull | TE | Out | Foot | |
| Matt Henningsen | DT | Out | Achilles | |
| Johnny Walker Jr. | DE | Out | Lower Body | |
| Dre Greenlaw | LB | Questionable | Hamstring | |
| Karene Reid | LB | Questionable | Hamstring | |
| Drew Sanders | LB | Out | Foot | |
| Justin Strnad | LB | Probable | Foot | |
| Brandon Jones | S | Out | Pectoral | |
| Riley Moss | CB | Probable | Ankle | |
| Kansas City Chiefs v DEN, Thursday, 8:15PM ET | ||||
| Patrick Mahomes II | QB | Out | Knee | |
| Gardner Minshew | QB | Out | Knee | |
| Keaontay Ingram | RB | Out | Undisclosed | |
| Nikko Remigio | WR | Probable | Knee | |
| Rashee Rice | WR | Questionable | Concussion | |
| Tyquan Thornton | WR | Questionable | Concussion | |
| Jake Briningstool | TE | Questionable | Hamstring | |
| Noah Gray | TE | Probable | Shoulder | |
| Derrick Nnadi | DT | Questionable | Illness | |
| Omarr Norman-Lott | DT | Out | Knee | |
| Felix Anudike-Uzomah | DE | Out | Hamstring | |
| Janarius Robinson | DE | Out | Foot | |
| Leo Chenal | LB | Out | Shoulder | |
| Brandon George | LB | Out | Undisclosed | |
| Deon Bush | S | Out | Achilles | |
| Mike Edwards | S | Probable | Shoulder | |
| Kristian Fulton | CB | Probable | Knee/wrist | |
| Nazeeh Johnson | CB | Questionable | Shoulder | |
| Trent McDuffie | CB | Questionable | Knee | |
| Chris Roland-Wallace | CB | Out | Back | |
| Eric Scott Jr. | CB | Out | Knee | |
| Jaylen Watson | CB | Questionable | Groin | |
| Houston Texans @ LAC, Saturday, 4:30PM ET | ||||
| Woody Marks | RB | Questionable | Ankle | |
| Joe Mixon | RB | Out | Foot | |
| Tank Dell | WR | Out | Knee | |
| Justin Watson | WR | Questionable | Undisclosed | |
| Brevin Jordan | TE | Out | Knee | |
| Layne Pryor | TE | Out | Undisclosed | |
| Marcus Harris | DL | Questionable | Knee | |
| Mario Edwards Jr | DT | Out | Pectoral | |
| Folorunso Fatukasi | DT | Out | Shoulder | |
| Kyonte Hamilton | DT | Out | Ankle | |
| Kurt Hinish | DT | Out | Undisclosed | |
| Tim Settle Jr. | DT | Out | Foot | |
| Darrell Taylor | DE | Questionable | Ankle | |
| Azeez Al-Shaair | LB | Questionable | Ankle/knee | |
| Jake Hansen | LB | Questionable | Chest | |
| Jaylen Reed | S | Out | Forearm | |
| M.J. Stewart | S | Out | Knee | |
| Jimmie Ward | S | Out | Foot | |
| Ajani Carter | CB | Questionable | Hamstring | |
| Jaylin Smith | CB | Out | Undisclosed | |
| Los Angeles Chargers v HOU, Saturday, 4:30PM ET | ||||
| Najee Harris | RB | Out | Achilles | |
| Kimani Vidal | RB | Questionable | Neck | |
| Derius Davis | WR | Questionable | Ankle | |
| Tucker Fisk | TE | Out | Ankle | |
| Josh Fuga | DT | Out | Undisclosed | |
| Bud Dupree | DE | Questionable | Back | |
| Junior Colson | LB | Out | Shoulder | |
| Denzel Perryman | LB | Out | Suspended | |
| RJ Mickens | S | Questionable | Shoulder | |
| Donte Jackson | CB | Questionable | Groin | |
| Jordan Oladokun | CB | Out | Undisclosed | |
| Eric Rogers | CB | Out | Undisclosed | |
| Benjamin St-Juste | CB | Questionable | Shoulder | |
| Baltimore Ravens @ GB, Saturday, 8:00PM ET | ||||
| Lamar Jackson | QB | Questionable | Back | |
| Justice Hill | RB | Out | Neck | |
| Dayton Wade | WR | Out | Undisclosed | |
| Taven Bryan | DT | Out | Knee | |
| Nnamdi Madubuike | DT | Out | Neck | |
| Broderick Washington Jr. | DT | Out | Ankle | |
| Adisa Isaac | DE | Out | Elbow | |
| Teddye Buchanan | LB | Out | Knee | |
| Jay Higgins IV | LB | Questionable | Knee | |
| Chandler Martin | LB | Out | Knee (acl) | |
| Chidobe Awuzie | CB | Questionable | Foot | |
| Bilhal Kone | CB | Out | Knee | |
| Robert Longerbeam | CB | Out | Knee | |
| Green Bay Packers v BAL, Saturday, 8:00PM ET | ||||
| Jordan Love | QB | Questionable | Concussion | |
| Malik Willis | QB | Questionable | Shoulder | |
| Josh Jacobs | RB | Questionable | Knee | |
| MarShawn Lloyd | RB | Out | Calf/hamstring | |
| Romeo Doubs | WR | Questionable | Wrist | |
| John FitzPatrick | TE | Out | Achilles | |
| Tucker Kraft | TE | Out | Knee | |
| Josh Whyle | TE | Questionable | Concussion | |
| Devonte Wyatt | DT | Out | Ankle | |
| Micah Parsons | DE | Out | Knee | |
| Nick Niemann | LB | Out | Pectoral | |
| Kristian Welch | LB | Questionable | Ankle | |
| Evan Williams | S | Questionable | Knee | |
| Arizona Cardinals @ CIN, Sunday, 1:00PM ET | ||||
| Joey Blount | FS | Out | Neck | |
| Kyler Murray | QB | Out | Foot | |
| Trey Benson | RB | Out | Knee | |
| James Conner | RB | Out | Foot | |
| Bam Knight | RB | Out | Ankle | |
| Andre Baccellia | WR | Out | Neck | |
| Greg Dortch | WR | Out | Chest | |
| Simi Fehoko | WR | Out | Wrist | |
| Zay Jones | WR | Out | Achilles | |
| Tip Reiman | TE | Out | Ankle | |
| Travis Vokolek | TE | Out | Neck | |
| Bilal Nichols | DT | Out | Knee | |
| Walter Nolen III | DT | Out | Knee | |
| L.J. Collier | DE | Questionable | Knee | |
| Josh Sweat | DE | Questionable | Ankle | |
| J.J. Russell | LB | Out | Concussion | |
| Mack Wilson Sr. | LB | Out | Ribs | |
| Dadrion Taylor-Demerson | S | Questionable | Ankle | |
| Jalen Thompson | S | Questionable | Hamstring | |
| Sean Murphy-Bunting | CB | Out | Knee | |
| Darren Hall | CB | Questionable | Concussion | |
| Max Melton | CB | Questionable | Heel | |
| Starling Thomas V | CB | Out | Knee | |
| Garrett Williams | CB | Out | Achilles | |
| Carolina Panthers v SEA, Sunday, 1:00PM ET | ||||
| Jonathon Brooks | RB | Out | Knee | |
| David Moore | WR | Questionable | Elbow | |
| Popo Aumavae | DT | Out | Achilles | |
| Tershawn Wharton | DT | Questionable | Hamstring | |
| Patrick Jones II | DE | Out | Back | |
| Trevin Wallace | LB | Questionable | Shoulder | |
| Corey Thornton | DB | Out | Leg | |
| Damarri Mathis | CB | Out | Knee | |
| Robert Rochell | CB | Questionable | Ankle | |
| Cincinnati Bengals v ARI, Sunday, 1:00PM ET | ||||
| Charlie Jones | WR | Questionable | Ankle | |
| Erick All Jr. | TE | Out | Knee | |
| Noah Fant | TE | Questionable | Ankle | |
| Cam Grandy | TE | Questionable | Collarbone | |
| Kris Jenkins Jr. | DT | Out | Ankle | |
| Trey Hendrickson | DE | Out | Hip/pelvis | |
| Joseph Ossai | DE | Questionable | Ankle | |
| Brian Asamoah II | LB | Out | Knee | |
| PJ Jules | S | Questionable | Ankle | |
| Cam Taylor-Britt | CB | Out | Foot | |
| Marco Wilson | CB | Out | Hamstring | |
| Cleveland Browns v PIT, Sunday, 1:00PM ET | ||||
| Deshaun Watson | QB | Out | Achilles | |
| Jerome Ford | RB | Out | Shoulder | |
| Quinshon Judkins | RB | Out | Knee | |
| Dylan Sampson | RB | Questionable | Hand | |
| DeAndre Carter | WR | Out | Knee | |
| David Njoku | TE | Questionable | Knee | |
| Maliek Collins | DT | Out | Quadricep | |
| Sam Kamara | DE | Questionable | Elbow | |
| Julian Okwara | LB | Out | Undisclosed | |
| Jeremiah Owusu-Koramoah | LB | Out | Neck | |
| Winston Reid | LB | Questionable | Back | |
| Nathaniel Watson | LB | Out | Biceps | |
| Dom Jones | DB | Out | Knee | |
| Martin Emerson Jr | CB | Out | Achilles | |
| Anthony Kendall | CB | Out | Undisclosed | |
| Denzel Ward | CB | Questionable | Calf | |
| Indianapolis Colts v JAX, Sunday, 1:00PM ET | ||||
| Daniel Jones | QB | Out | Achilles | |
| Anthony Richardson Sr. | QB | Questionable | Eye | |
| Salvon Ahmed | RB | Out | Ankle | |
| DJ Giddens | RB | Out | Gameday Inactive | |
| Ashton Dulin | WR | Out | Hamstring | |
| Anthony Gould | WR | Questionable | Foot | |
| D.J. Montgomery | WR | Out | Undisclosed | |
| Will Mallory | TE | Out | Gameday Inactive | |
| Drew Ogletree | TE | Questionable | Neck | |
| Spencer Shrader | PK | Out | Knee | |
| JT Tuimoloau | DE | Questionable | Oblique | |
| Jaylon Carlies | LB | Out | Gameday Inactive | |
| Jacob Phillips | LB | Out | Bicep | |
| Daniel Scott | S | Questionable | Knee | |
| Hunter Wohler | S | Out | Foot | |
| Sauce Gardner | CB | Questionable | Calf | |
| Mike Hilton | CB | Out | Shoulder | |
| Chris Lammons | CB | Out | Foot | |
| Reuben Lowery III | CB | Out | Gameday Inactive | |
| Justin Walley | CB | Out | Knee | |
| Charvarius Ward | CB | Out | Concussion | |
| Jacksonville Jaguars @ IND, Sunday, 1:00PM ET | ||||
| Bhayshul Tuten | RB | Out | Finger | |
| Joshua Cephus | WR | Out | Undisclosed | |
| Travis Hunter | WR | Out | Knee | |
| Danny Striggow | DE | Questionable | Ankle | |
| Jack Kiser | LB | Out | Hamstring | |
| Jalen McLeod | LB | Questionable | Ankle | |
| Caleb Ransaw | S | Out | Undisclosed | |
| Greg Newsome II | CB | Questionable | Shoulder | |
| Miami Dolphins v TB, Sunday, 1:00PM ET | ||||
| Alexander Mattison | RB | Out | Neck | |
| Dee Eskridge | WR | Questionable | Toe | |
| Tyreek Hill | WR | Out | Left Knee | |
| Jalin Conyers | TE | Out | Leg | |
| Jason Sanders | PK | Questionable | Hip | |
| Caleb Johnson | LB | Out | Shoulder | |
| Elijah Campbell | DB | Out | Ankle/knee | |
| Jordan Colbert | S | Out | Neck | |
| Minkah Fitzpatrick | S | Questionable | Calf | |
| JuJu Brents | CB | Out | Ankle | |
| Artie Burns | CB | Out | Knee | |
| Storm Duck | CB | Out | Knee | |
| Isaiah Johnson | CB | Questionable | Knee | |
| Kader Kohou | CB | Out | Knee | |
| Jason Maitre | CB | Out | Undisclosed | |
| Kendall Sheffield | CB | Out | Undisclosed | |
| New England Patriots @ NYJ, Sunday, 1:00PM ET | ||||
| Brock Lampe | FB | Out | Undisclosed | |
| Antonio Gibson | RB | Out | Knee | |
| TreVeyon Henderson | RB | Questionable | Head | |
| Terrell Jennings | RB | Out | Concussion | |
| Lan Larison | RB | Out | Undisclosed | |
| Deneric Prince | RB | Out | Undisclosed | |
| Craig Reynolds | RB | Out | Undisclosed | |
| Thomas Odukoya | TE | Out | Undisclosed | |
| Isaiah Iton | DL | Out | Hip | |
| Joshua Farmer | DT | Questionable | Hamstring | |
| Jaquelin Roy | DT | Out | Undisclosed | |
| Milton Williams | DT | Questionable | Ankle | |
| Darius Harris | LB | Out | Undisclosed | |
| Robert Spillane | LB | Questionable | Ankle | |
| Alex Austin | CB | Out | Undisclosed | |
| Marcellas Dial Jr. | CB | Out | Acl | |
| Charles Woods | CB | Questionable | Ankle | |
| New Orleans Saints @ TEN, Sunday, 1:00PM ET | ||||
| Hunter Dekkers | QB | Out | Shoulder | |
| Alvin Kamara | RB | Questionable | Knee/ankle | |
| Kendre Miller | RB | Out | Knee | |
| Devin Neal | RB | Out | Hamstring | |
| Bub Means | WR | Out | Ankle | |
| Trey Palmer | WR | Out | Ankle | |
| Ja'Lynn Polk | WR | Out | Shoulder | |
| Devaughn Vele | WR | Out | Shoulder | |
| Zaire Mitchell-Paden | TE | Questionable | Knee | |
| Foster Moreau | TE | Out | Ankle | |
| Mason Pline | TE | Out | Undisclosed | |
| Bryan Bresee | DT | Out | Knee | |
| Vernon Broughton | DT | Out | Hip | |
| Julian Blackmon | S | Out | Labrum Tear | |
| New York Jets v NE, Sunday, 1:00PM ET | ||||
| Justin Fields | QB | Questionable | Knee | |
| Braelon Allen | RB | Out | Knee | |
| Keilan Robinson | RB | Out | Undisclosed | |
| Irvin Charles | WR | Out | Knee | |
| Josh Reynolds | WR | Out | Hip | |
| Garrett Wilson | WR | Out | Knee | |
| Mason Taylor | TE | Questionable | Neck | |
| Jay Tufele | DT | Questionable | Foot | |
| Eric Watts | DT | Questionable | Concussion | |
| Tyler Baron | DE | Out | Knee | |
| Kiko Mauigoa | LB | Questionable | Neck | |
| Marcelino McCrary-Ball | LB | Out | Hamstring | |
| Tony Adams | S | Out | Groin | |
| Andre Cisco | S | Out | Pectoral | |
| Kris Boyd | CB | Out | Shoulder | |
| Jarvis Brownlee Jr. | CB | Out | Hip | |
| Isaiah Oliver | CB | Out | Knee | |
| Azareye'h Thomas | CB | Out | Shoulder | |
| Pittsburgh Steelers @ CLE, Sunday, 1:00PM ET | ||||
| Skylar Thompson | QB | Out | Hamstring | |
| DK Metcalf | WR | Out | Suspended | |
| Donald Parham Jr | TE | Out | Achilles | |
| Daniel Ekuale | DT | Out | Suspension | |
| Dean Lowry | DT | Out | Knee | |
| Jacob Slade | DT | Out | Undisclosed | |
| Nick Herbig | DE | Questionable | Hamstring | |
| Isaiahh Loudermilk | DE | Out | Ankle | |
| T.J. Watt | DE | Questionable | Lung | |
| DeShon Elliott | S | Out | Knee | |
| Miles Killebrew | S | Out | Knee | |
| Brandin Echols | CB | Questionable | Groin | |
| Donte Kent | CB | Questionable | Ankle/knee | |
| James Pierre | CB | Questionable | Calf | |
| Cory Trice Jr. | CB | Out | Hamstring | |
| Seattle Seahawks @ CAR, Sunday, 1:00PM ET | ||||
| George Holani | RB | Out | Hamstring | |
| Kenny McIntosh | RB | Out | Knee | |
| Jacardia Wright | RB | Out | Undisclosed | |
| Tyrone Broden | WR | Out | Undisclosed | |
| Tory Horton | WR | Out | Shin | |
| Elijah Arroyo | TE | Out | Knee | |
| Derick Hall | DE | Out | Suspended | |
| Chazz Surratt | LB | Out | Ankle | |
| Coby Bryant | S | Questionable | Knee | |
| Nick Emmanwori | S | Questionable | Concussion | |
| AJ Finley | S | Out | Knee | |
| Riq Woolen | CB | Questionable | Knee | |
| Tampa Bay Buccaneers @ MIA, Sunday, 1:00PM ET | ||||
| Jaden Smith | WR | Out | Undisclosed | |
| Ko Kieft | TE | Out | Leg | |
| Jayson Jones | DL | Out | Undisclosed | |
| Calijah Kancey | DT | Out | Pectoral | |
| Anthony Nelson | DE | Questionable | Knee | |
| David Walker | LB | Out | Knee | |
| JJ Roberts | S | Out | Knee | |
| Zyon McCollum | CB | Out | Hip | |
| Tennessee Titans v NO, Sunday, 1:00PM ET | ||||
| Will Levis | QB | Out | Shoulder | |
| Blake Watson | RB | Out | Undisclosed | |
| Bryce Oliver | WR | Questionable | Knee | |
| Calvin Ridley | WR | Out | Fibula | |
| Joel Wilson | TE | Out | Undisclosed | |
| Ali Gaye | DE | Questionable | Knee | |
| Oluwafemi Oladejo | DE | Questionable | Calf | |
| Cedric Gray | LB | Questionable | Concussion | |
| Anfernee Orji | LB | Out | Knee | |
| Mike Brown | S | Out | Ankle | |
| Kevin Winston Jr. | S | Out | Hamstring | |
| Xavier Woods | S | Out | Hamstring | |
| L'Jarius Sneed | CB | Out | Quadricep | |
| Las Vegas Raiders v NYG, Sunday, 4:05PM ET | ||||
| Tyler Lockett | WR | Questionable | Wrist | |
| JJ Pegues | DT | Questionable | Hand | |
| Brennan Jackson | DE | Out | Foot | |
| Kyu Blu Kelly | CB | Out | Knee | |
| New York Giants @ LV, Sunday, 4:05PM ET | ||||
| Cam Skattebo | RB | Out | Ankle | |
| Beaux Collins | WR | Questionable | Neck | |
| Da'Quan Felton | WR | Out | Undisclosed | |
| Bryce Ford-Wheaton | WR | Out | Achilles | |
| Malik Nabers | WR | Out | Knee | |
| Thomas Fidone II | TE | Out | Foot | |
| Graham Gano | PK | Out | Neck | |
| Rakeem Nuñez-Roches Sr. | DT | Questionable | Ankle | |
| Victor Dimukeje | DE | Out | Knee | |
| Kayvon Thibodeaux | DE | Out | Shoulder | |
| Chris Board | LB | Out | Chest | |
| Demetrius Flannigan-Fowles | LB | Questionable | Illness | |
| Micah McFadden | LB | Out | Lower Leg | |
| Anthony Johnson Jr. | S | Out | Undisclosed | |
| Cor'Dale Flott | CB | Questionable | Knee | |
| Nic Jones | CB | Out | Shoulder | |
| TJ Moore | CB | Out | Leg | |
| Buffalo Bills v PHI, Sunday, 4:25PM ET | ||||
| Josh Allen | QB | Questionable | Foot | |
| Curtis Samuel | WR | Out | Elbow/knee | |
| Tyler Bass | PK | Out | Left Hip/groin | |
| Matt Prater | PK | Questionable | Right Quad | |
| DeWayne Carter | DT | Out | Achilles | |
| DaQuan Jones | DT | Questionable | Calf | |
| Ed Oliver | DT | Out | Bicep | |
| Jordan Phillips | DT | Questionable | Ankle | |
| Michael Hoecht | DE | Out | Achilles | |
| Landon Jackson | DE | Out | Knee | |
| Shaq Thompson | LB | Questionable | Neck | |
| Damar Hamlin | S | Out | Pectoral | |
| Wande Owens | S | Out | Undisclosed | |
| Jordan Poyer | S | Questionable | Hamstring | |
| Taylor Rapp | S | Out | Knee | |
| Darius Slay | CB | Out | Did Not Report | |
| Dorian Strong | CB | Out | Neck | |
| Philadelphia Eagles @ BUF, Sunday, 4:25PM ET | ||||
| Johnny Wilson | WR | Out | Knee/ankle | |
| Cameron Latu | TE | Questionable | Stinger | |
| Jalen Carter | DT | Questionable | Shoulders | |
| Azeez Ojulari | DE | Out | Hamstring | |
| Ogbo Okoronkwo | DE | Out | Triceps | |
| Nakobe Dean | LB | Questionable | Hamstring | |
| Ben VanSumeren | LB | Out | Knee | |
| Andrew Mukuba | S | Out | Ankle | |
| Chicago Bears @ SF, Sunday, 8:20PM ET | ||||
| Deion Hankins | RB | Out | Knee | |
| Roschon Johnson | RB | Out | Thumb | |
| Luther Burden III | WR | Questionable | Ankle | |
| Rome Odunze | WR | Questionable | Foot | |
| Nikola Kalinic | TE | Out | Undisclosed | |
| Dayo Odeyingbo | DE | Out | Achilles | |
| Shemar Turner | DE | Out | Knee | |
| Amen Ogbongbemiga | LB | Questionable | Hamstring | |
| C.J. Gardner-Johnson | S | Questionable | Knee | |
| Zah Frazier | CB | Out | Personal | |
| Kyler Gordon | CB | Out | Groin | |
| Terell Smith | CB | Out | Knee | |
| San Francisco 49ers v CHI, Sunday, 8:20PM ET | ||||
| Kurtis Rourke | QB | Questionable | Knee | |
| Isaac Guerendo | RB | Out | Gameday Inactive | |
| Patrick Taylor Jr. | RB | Out | Shoulder | |
| Brandon Aiyuk | WR | Out | Knee | |
| Jacob Cowing | WR | Out | Hamstring | |
| Ricky Pearsall | WR | Questionable | Knee/ankle | |
| Trent Taylor | WR | Out | Undisclosed | |
| George Kittle | TE | Questionable | Ankle | |
| Kevin Givens | DT | Out | Gameday Inactive | |
| Robert Beal Jr. | DE | Out | Gameday Inactive | |
| Nick Bosa | DE | Out | Knee | |
| Tarron Jackson | DE | Out | Neck | |
| Mykel Williams | DE | Out | Knee | |
| Tatum Bethune | LB | Questionable | Ankle | |
| Nick Martin | LB | Out | Concussion | |
| Curtis Robinson | LB | Out | Gameday Inactive | |
| Fred Warner | LB | Out | Ankle | |
| Renardo Green | CB | Questionable | Neck | |
| Tre Tomlinson | CB | Out | Undisclosed | |
| Chase Lucas | CB | Out | Gameday Inactive | |
| Jakob Robinson | CB | Out | Forearm | |
| Atlanta Falcons v LAR, Monday, 8:15PM ET | ||||
| Emory Jones | QB | Out | Concussion | |
| Michael Penix Jr. | QB | Out | Knee | |
| KhaDarel Hodge | WR | Out | Shoulder | |
| Sam Roberts | DT | Out | Knee/ankle | |
| Zach Harrison | DE | Out | Knee | |
| DeAngelo Malone | DE | Out | Ankle | |
| Bralen Trice | DE | Out | Knee | |
| Troy Andersen | LB | Out | Knee | |
| Billy Bowman Jr. | S | Out | Achilles | |
| DeMarcco Hellams | S | Out | Hamstring | |
| Malik Verdon | S | Out | Undisclosed | |
| Mike Hughes | CB | Questionable | Ankle | |
| Clark Phillips III | CB | Out | Triceps/illness | |
| Los Angeles Rams @ ATL, Monday, 8:15PM ET | ||||
| Davante Adams | WR | Questionable | Knee/hamstring | |
| Tyler Higbee | TE | Questionable | Ankle | |
| Keir Thomas | DE | Out | Undisclosed | |
| Quentin Lake | S | Out | Elbow | |
| Roger McCreary | CB | Out | Hip | |