| Player | TM | Wk15 | Wk16 | Wk17 | Wk18 | Wk19 | Wk20 | Wk21 | Targ | T/TmG | T/G | REC | YD | Y/R | TD | Rec% |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Brandon Aiyuk | SF | 13 | 2 | 0 | - | - | - | - | 97 | 6.1 | 6.1 | 60 | 748 | 12.5 | 5 | 61.9 |
| Chris Conley | SF | 3 | 3 | 9 | - | - | - | - | 63 | 3.9 | 3.9 | 40 | 471 | 11.8 | 2 | 63.5 |
| Kyle Juszczyk | SF | 2 | 3 | 2 | - | - | - | - | 30 | 1.9 | 1.9 | 19 | 202 | 10.6 | 4 | 63.3 |
| Marqise Lee | SF | 0 | 0 | 0 | - | - | - | - | 0 | 0.0 | 0.0 | 0 | 0 | 0.0 | 0 | 0.0 |
| Christian McCaffrey | SF | 0 | 0 | 0 | - | - | - | - | 19 | 1.2 | 1.9 | 17 | 149 | 8.8 | 1 | 89.5 |