| Player | TM | Wk1 | Wk2 | Wk3 | Targ | T/TmG | T/G | REC | YD | Y/R | TD | Rec% |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Deebo Samuel | SF | 12 | 8 | 10 | 30 | 10.0 | 10.0 | 20 | 334 | 16.7 | 1 | 66.7 |
| George Kittle | SF | 5 | 4 | 9 | 18 | 6.0 | 6.0 | 15 | 187 | 12.5 | 0 | 83.3 |
| Christian McCaffrey | SF | 9 | 6 | 2 | 17 | 5.7 | 5.7 | 16 | 163 | 10.2 | 0 | 94.1 |
| Kyle Juszczyk | SF | 1 | 3 | 4 | 8 | 2.7 | 2.7 | 7 | 59 | 8.4 | 1 | 87.5 |
| Brandon Aiyuk | SF | 0 | 2 | 6 | 8 | 2.7 | 2.7 | 5 | 43 | 8.6 | 1 | 62.5 |