NOTE: only players with at least 2 targets per week are shown.
| Player | TM | Wk9 | Wk10 | Wk11 | Wk12 | Wk13 | Wk14 | Wk15 | Targ | T/TmG | T/G | REC | YD | Y/R | TD | Rec% |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Kyle Juszczyk | SF | 2 | 6 | - | 2 | 3 | 4 | 4 | 33 | 2.4 | 2.8 | 24 | 220 | 9.2 | 1 | 72.7 |
| Christian McCaffrey | SF | 6 | 7 | - | 5 | 6 | 4 | 7 | 101 | 7.2 | 7.2 | 73 | 592 | 8.1 | 5 | 72.3 |
| Trent Taylor | SF | 3 | dnp | - | 3 | 6 | 3 | 5 | 54 | 3.9 | 4.2 | 38 | 382 | 10.1 | 1 | 70.4 |
| George Kittle | SF | 5 | dnp | - | 2 | 3 | 2 | 5 | 54 | 3.9 | 4.2 | 36 | 373 | 10.4 | 1 | 66.7 |
| Marqise Lee | SF | 12 | 11 | - | 2 | 10 | 6 | 0 | 96 | 6.9 | 6.9 | 56 | 702 | 12.5 | 3 | 58.3 |
