NOTE: only players with at least 2 targets per week are shown.
| Player | TM | Wk10 | Wk11 | Wk12 | Wk13 | Wk14 | Wk15 | Wk16 | Targ | T/TmG | T/G | REC | YD | Y/R | TD | Rec% |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Kyle Juszczyk | SF | 6 | - | 2 | 3 | 4 | 4 | 5 | 38 | 2.5 | 2.9 | 29 | 296 | 10.2 | 1 | 76.3 |
| Christian McCaffrey | SF | 7 | - | 5 | 6 | 4 | 7 | 4 | 105 | 7.0 | 7.0 | 75 | 611 | 8.1 | 5 | 71.4 |
| Trent Taylor | SF | dnp | - | 3 | 6 | 3 | 5 | 4 | 58 | 3.9 | 4.1 | 41 | 401 | 9.8 | 2 | 70.7 |
| George Kittle | SF | dnp | - | 2 | 3 | 2 | 5 | 3 | 57 | 3.8 | 4.1 | 39 | 415 | 10.6 | 2 | 68.4 |
| Marqise Lee | SF | 11 | - | 2 | 10 | 6 | 0 | dnp | 96 | 6.4 | 6.9 | 56 | 702 | 12.5 | 3 | 58.3 |
