NOTE: only players with at least 2 targets per week are shown.
| Player | TM | Wk13 | Wk14 | Wk15 | Wk16 | Wk17 | Wk18 | Wk19 | Targ | T/TmG | T/G | REC | YD | Y/R | TD | Rec% |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Christian McCaffrey | SF | dnp | dnp | 0 | dnp | dnp | dnp | dnp | 41 | 2.3 | 4.1 | 37 | 343 | 9.3 | 1 | 90.2 |
| Kyle Juszczyk | SF | 3 | 2 | 1 | 5 | 2 | 0 | 3 | 40 | 2.2 | 2.2 | 32 | 311 | 9.7 | 1 | 80.0 |
| George Kittle | SF | 12 | 15 | 6 | 3 | 2 | 7 | 3 | 97 | 5.4 | 6.5 | 72 | 928 | 12.9 | 6 | 74.2 |
| Brandon Aiyuk | SF | 6 | 11 | 2 | 5 | 6 | 7 | 6 | 91 | 5.1 | 5.1 | 61 | 892 | 14.6 | 5 | 67.0 |
| Deebo Samuel | SF | 0 | 1 | 5 | 11 | 6 | 6 | 3 | 124 | 6.9 | 6.9 | 80 | 1443 | 18.0 | 6 | 64.5 |
