| Name | Team | Opp | CMP | ATT | PYD | PTD | INT | RSH | YD | TD | FPT | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Josh Allen | BUF | at DET | 23 | 34 | 283 | 2.25 | 0.90 | 7 | 48 | 0.45 | 26.0 | |
| 2 | Patrick Mahomes II | KC | vs LAR | 25 | 36 | 297 | 2.37 | 0.69 | 4 | 23 | 0.17 | 23.3 | |
| 3 | Jalen Hurts | PHI | vs GB | 18 | 27 | 218 | 1.57 | 0.52 | 11 | 46 | 0.70 | 22.8 | |
| 4 | Tua Tagovailoa | MIA | vs HOU | 23 | 32 | 296 | 2.29 | 0.63 | 3 | 8 | 0.10 | 21.1 | |
| 5 | Lamar Jackson | BAL | at JAX | 18 | 27 | 203 | 1.52 | 0.77 | 10 | 61 | 0.32 | 20.7 |