NOTE: only players with at least 2 targets per week are shown.
| Player | TM | Wk11 | Wk12 | Wk13 | Wk14 | Wk15 | Wk16 | Wk17 | Targ | T/TmG | T/G | REC | YD | Y/R | TD | Rec% |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Kyle Juszczyk | SF | - | 2 | 3 | 4 | 4 | 5 | 4 | 42 | 2.6 | 3.0 | 33 | 315 | 9.5 | 1 | 78.6 |
| Trent Taylor | SF | - | 3 | 6 | 3 | 5 | 4 | 2 | 60 | 3.8 | 4.0 | 43 | 430 | 10.0 | 2 | 71.7 |
| Christian McCaffrey | SF | - | 5 | 6 | 4 | 7 | 4 | 8 | 113 | 7.1 | 7.1 | 80 | 651 | 8.1 | 5 | 70.8 |
| George Kittle | SF | - | 2 | 3 | 2 | 5 | 3 | 6 | 63 | 3.9 | 4.2 | 43 | 515 | 12.0 | 2 | 68.3 |
| Marqise Lee | SF | - | 2 | 10 | 6 | 0 | dnp | dnp | 96 | 6.0 | 6.9 | 56 | 702 | 12.5 | 3 | 58.3 |
