Isaac Guerendo
RB
San Francisco 49ers
Age 26
Height/Weight 6'0", 221 Lbs
College Louisville
Drafted Round 4 Pick 129
Loading Player Profile
Week 6
This player is not ranked by any Footballguys Staff.
Dynasty
Rankings
Footballguys Consensus
RB104
Andy Hicks
RB101
Sigmund Bloom
RB96
Jeff Haseley
RB93
Jeff Bell
RB111
Craig Lakins
RB103
Dave Kluge
RB108
Ryan Weisse
RB97
Corey Spala
RB92
How to Handle Josh Jacobs and the Packers' Backfield
Bob Harris
With Josh Jacobs facing serious legal issues, let's examine the Packers' backfield options.
05/27/26
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Schedule
San Francisco 49ers Schedule
| Week | Date & Time | Opponent | TV | Spread/Total | Weather |
|---|---|---|---|---|---|
| 1 |
Thursday, September 10 8:35 PM |
@
Los Angeles Rams
|
NFLX |
-3.5
O/U 47.5
|
Clear Sky
|
| 2 |
Sunday, September 20 4:25 PM |
vs
Miami Dolphins
|
FOX |
-13.0
O/U 45.0
|
Overcast Clouds
|
| 3 |
Sunday, September 27 4:05 PM |
vs
Arizona Cardinals
|
FOX |
-7.5
O/U 49.0
|
Scattered Clouds
|
| 4 |
Sunday, October 4 4:25 PM |
vs
Denver Broncos
|
CBS/P |
-3.0
O/U 48.5
|
Clear Sky
|
| 5 |
Sunday, October 11 4:25 PM |
@
Seattle Seahawks
|
FOX |
-3.0
O/U 47.0
|
Clear Sky
|
| 6 |
Monday, October 19 8:15 PM |
vs
Washington Commanders
|
ABC/E |
-7.5
O/U 51.5
|
Clear Sky
|
| 7 |
Sunday, October 25 1:00 PM |
@
Atlanta Falcons
|
FOX | ||
| 9 |
Sunday, November 8 4:05 PM |
vs
Las Vegas Raiders
|
CBS/P | ||
| 10 |
Sunday, November 15 4:25 PM |
@
Dallas Cowboys
|
FOX | ||
| 11 |
Sunday, November 22 8:20 PM |
vs
Minnesota Vikings
|
NBC/P | ||
| 12 |
Sunday, November 29 4:25 PM |
vs
Seattle Seahawks
|
FOX | ||
| 13 |
Sunday, December 6 1:00 PM |
@
New York Giants
|
FOX | ||
| 14 |
Sunday, December 13 4:25 PM |
vs
Los Angeles Rams
|
FOX | ||
| 15 |
Thursday, December 17 8:15 PM |
@
Los Angeles Chargers
|
AMZN | ||
| 16 |
Sunday, December 27 4:25 PM |
@
Kansas City Chiefs
|
CBS/P | ||
| 17 |
Sunday, January 3 8:20 PM |
vs
Philadelphia Eagles
|
NBC/P | ||
| 18 |
Sunday, January 10 --:-- |
@
Arizona Cardinals
|
Career Stats
| YR | TM | G | RSH | RushYD | Y/Rush | RushTD | TGT | REC | RecYD | RecTD | Rank | VBD | ADP |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024 | SF | 16 | 84 | 420 | 5.0 | 4 | 16 | 15 | 152 | 0 | |||
| 2025 | SF | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| Total | 30 | 84 | 420 | 5.0 | 4 | 16 | 15 | 152 | 0 | 0 |
Game Logs
| YR | WK | OPP | oSNAP | RSH | YD | TD | TARG | REC | YD | TD |
|---|---|---|---|---|---|---|---|---|---|---|
| 2025 | TEN | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| 2025 | 1 | SEA | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2025 | 2 | NO | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2025 | 3 | ARI | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2025 | 4 | JAX | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2025 | 5 | LAR | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2025 | 6 | TB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2025 | 7 | ATL | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2025 | 8 | HOU | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2025 | 9 | NYG | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2025 | 10 | LAR | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2025 | 11 | ARI | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2025 | 12 | CAR | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2025 | 13 | CLE | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2025 | 15 | TEN | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2024 | TB | 227 | 84 | 420 | 4 | 16 | 15 | 152 | 0 | |
| 2024 | 1 | NYJ | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2024 | 2 | MIN | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2024 | 3 | LAR | 10 | 5 | 19 | 0 | 0 | 0 | 0 | 0 |
| 2024 | 4 | NE | 5 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2024 | 5 | ARI | 9 | 5 | 22 | 0 | 0 | 0 | 0 | 0 |
| 2024 | 6 | SEA | 17 | 10 | 99 | 0 | 0 | 0 | 0 | 0 |
| 2024 | 7 | KC | 5 | 1 | 2 | 0 | 1 | 1 | 5 | 0 |
| 2024 | 8 | DAL | 43 | 14 | 85 | 1 | 4 | 3 | 17 | 0 |
| 2024 | 10 | TB | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2024 | 11 | SEA | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2024 | 12 | GB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2024 | 13 | BUF | 11 | 4 | 19 | 1 | 1 | 1 | -3 | 0 |
| 2024 | 14 | CHI | 34 | 15 | 78 | 2 | 2 | 2 | 50 | 0 |
| 2024 | 15 | LAR | 41 | 16 | 57 | 0 | 4 | 4 | 18 | 0 |
| 2024 | 17 | DET | 39 | 9 | 34 | 0 | 4 | 4 | 65 | 0 |
| 2024 | 18 | ARI | 4 | 2 | 5 | 0 | 0 | 0 | 0 | 0 |
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Sat Jul 25 14:28
Isaac Guerendo not cleared yet
San Francisco 49ers RB Isaac Guerendo (pectoral) was placed on the Active/Physically Unable to Perform list Saturday, July 25.