| Name | Team | Opp | CMP | ATT | PYD | PTD | INT | RSH | YD | TD | FPT | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jalen Hurts | PHI | at NYG | 19 | 29 | 235 | 1.63 | 0.45 | 11 | 53 | 0.67 | 24.4 | |
| 2 | Josh Allen | BUF | vs NYJ | 24 | 36 | 265 | 1.87 | 1.00 | 8 | 47 | 0.42 | 23.3 | |
| 3 | Joe Burrow | CIN | vs CLE | 23 | 34 | 278 | 2.00 | 0.70 | 5 | 20 | 0.35 | 21.8 | |
| 4 | Patrick Mahomes II | KC | at DEN | 24 | 37 | 283 | 2.01 | 0.69 | 4 | 23 | 0.15 | 21.2 | |
| 5 | Justin Herbert | LAC | vs MIA | 28 | 41 | 298 | 1.94 | 0.82 | 3 | 16 | 0.12 | 20.3 |