| Name | Team | Opp | CMP | ATT | PYD | PTD | INT | RSH | YD | TD | FPT | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Josh Allen | BUF | vs TEN | 26 | 37 | 267 | 2.12 | 0.82 | 7 | 39 | 0.42 | 24.0 | |
| 2 | Patrick Mahomes II | KC | vs LAC | 26 | 38 | 295 | 2.35 | 0.67 | 3 | 16 | 0.19 | 22.6 | |
| 3 | Jalen Hurts | PHI | vs MIN | 19 | 30 | 230 | 1.38 | 0.65 | 10 | 55 | 0.54 | 22.2 | |
| 4 | Lamar Jackson | BAL | vs MIA | 20 | 29 | 227 | 1.56 | 0.79 | 9 | 52 | 0.38 | 21.2 | |
| 5 | Kyler Murray | ARI | at LV | 23 | 35 | 251 | 1.64 | 0.80 | 6 | 33 | 0.31 | 20.2 |