| Rank | Name | Tm/Bye | Age | G | Cmp | Att | Cm% | PYd | Y/Att | PTD | Int | Rsh | Yd | TD | FantPt |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Patrick Mahomes II | KC/12 | 26 | 16.5 | 422.1 | 627.7 | 67.2 | 5237 | 8.34 | 40.4 | 9.3 | 63.2 | 302 | 2.7 | 460.55 |
| 2 | Josh Allen | BUF/7 | 25 | 16.6 | 398.2 | 595.5 | 66.9 | 4596 | 7.72 | 34.5 | 13.1 | 105.3 | 489 | 8.1 | 452.20 |
| 3 | Kyler Murray | ARI/12 | 24 | 16.6 | 390.9 | 586.7 | 66.6 | 4307 | 7.34 | 28.9 | 12.8 | 134.0 | 809 | 8.6 | 450.65 |
| 4 | Lamar Jackson | BAL/8 | 24 | 16.5 | 310.2 | 477.5 | 65.0 | 3720 | 7.79 | 29.7 | 10.8 | 164.0 | 984 | 7.1 | 435.00 |
| 5 | Tom Brady | TB/9 | 44 | 16.6 | 426.3 | 645.8 | 66.0 | 5152 | 7.98 | 41.0 | 13.2 | 30.4 | 31 | 2.0 | 423.50 |