| name | Wk 1 | Wk 2 | Wk 3 | Wk 4 | Wk 5 | Wk 6 | Wk 7 | Wk 8 | Wk 9 | Wk 10 | Wk 11 | Wk 12 | Wk 13 | Wk 14 | Wk 15 | Wk 16 | Wk 17 | Wk 18 | Wk 19 | Wk 20 | Wk 21 | total |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Kyle Juszczyk | 1 | 3 | 4 | 4 | 4 | 0 | 0 | 1 | 2 | 1 | 2 | 2 | 3 | 2 | 1 | 5 | 2 | 0 | 3 | 0 | 0 | 37 |
| JaMycal Hasty | 1 | 5 | 0 | 0 | 0 | 0 | 6 | 2 | 4 | 0 | 0 | 0 | 0 | 3 | 1 | 3 | 1 | 3 | 0 | 0 | 3 | 29 |
| Elijah Mitchell | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 5 | 0 | 0 | 6 | 3 | 0 | 0 | 0 | 2 | 0 | 2 | 4 | 3 | 20 |
| Jeff Wilson Jr. | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 8 |
| Trey Sermon | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 |
| Trenton Cannon | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Raheem Mostert | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Jacques Patrick | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| RB Totals | 2 | 10 | 7 | 4 | 6 | 0 | 6 | 3 | 11 | 1 | 5 | 9 | 6 | 5 | 4 | 11 | 5 | 3 | 5 | 4 | 6 | 98 |
| Deebo Samuel | 12 | 8 | 10 | 13 | 9 | 0 | 11 | 9 | 9 | 5 | 2 | 4 | 0 | 1 | 5 | 11 | 6 | 6 | 3 | 4 | 7 | 121 |
| Brandon Aiyuk | 0 | 2 | 6 | 3 | 4 | 0 | 1 | 7 | 8 | 4 | 7 | 6 | 6 | 11 | 2 | 5 | 6 | 7 | 6 | 1 | 8 | 85 |
| Jauan Jennings | 0 | 2 | 0 | 1 | 0 | 0 | 2 | 2 | 0 | 2 | 1 | 3 | 1 | 5 | 6 | 5 | 2 | 7 | 5 | 2 | 2 | 39 |
| Mohamed Sanu | 1 | 1 | 6 | 5 | 3 | 0 | 1 | 4 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 24 |
| Trent Sherfield | 3 | 3 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 1 | 0 | 2 | 1 | 2 | 0 | 0 | 20 |
| Travis Benjamin | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 4 |
| WR Totals | 16 | 16 | 22 | 24 | 19 | 0 | 17 | 22 | 20 | 11 | 10 | 14 | 12 | 17 | 14 | 21 | 16 | 22 | 17 | 7 | 18 | 293 |
| George Kittle | 5 | 4 | 9 | 10 | 0 | 0 | 0 | 0 | 8 | 7 | 4 | 2 | 12 | 15 | 6 | 3 | 2 | 7 | 3 | 6 | 5 | 94 |
| Charlie Woerner | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6 |
| Ross Dwelley | 0 | 0 | 0 | 1 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 |
| TE Totals | 5 | 4 | 9 | 11 | 3 | 0 | 4 | 2 | 8 | 7 | 4 | 3 | 12 | 15 | 6 | 3 | 2 | 7 | 3 | 7 | 5 | 105 |