Welcome back to NFL Prop Talk, highlighting the best Week 6 NFL player props!
We went 3-2 on last week's props, bringing our record to 10-12 for the 2025 NFL season. Getting this article for free is a great reason to sign up for the DFS package, as it's just a small taste of what we can offer!
Prop Talk is Footballguys' leading NFL player props weekly article. We will utilize a combination of Footballguys' fantastic tools, rankings, and projections, along with my insights, to help you determine whether a player will go over or under their weekly player prop number and potentially win some money.
Let's dive right into some Week 6 NFL player props.
Week 6 NFL Player Props
We'll be using many different sportsbooks for these NFL player prop lines. Our advice is to always line-shop at as many sportsbooks as possible to find the best possible line!
Keenan Allen Over/Under 19.5 Yards Longest Reception (Hard Rock Bet)
If you went into the 2025 season thinking the return of Allen to the Chargers and Justin Herbert meant that he was going to step right back into a familiar role, then pat yourself on the back right now. Allen has seamlessly reintegrated into the offense, with at least five catches in every game and a 20+ yard catch in three of five games.
With stud rookie RB Omarion Hampton on IR for a month, it's easy to think that the Chargers will pass the ball at an even higher rate than they have been against a Dolphins defense that has allowed outside receivers to feast against them.
PICK: Allen OVER 19.5 yards longest reception (-110)
Jaxon Smith-Njigba Over/Under 24.5 Yards Longest Reception (Hard Rock Bet)
Smith-Njigba has had a great time against seemingly every defense he's faced this season, but especially against defenses that primarily run zone coverage, like the Jacksonville Jaguars, who do so at a 78% rate, the sixth-highest in the NFL.
The third-year Seahawks' WR currently has a 34% target rate against zone and leads the NFL in fantasy points per route run against the coverage. He has also hit the over on this prop in every single matchup this season.
In this matchup, the Seahawks will still probably look to establish the run through RBs Ken Walker III and Zach Charbonnet, but the Jaguars are one of the best run defenses in the NFL and will look to shut the Seahawks down from that angle.
The Jaguars have allowed the most attempts of 20+ air yards and the second-most completions, so watch for Smith-Njigba to make moves downfield once again.
PICK: Smith-Njigba OVER 24.5 yards longest reception (-115)