Another week in the NFL brought yet another wave of injuries, and this one hit especially hard for fantasy managers. From lower-body strains to potential season-ending ligament damage, several key offensive contributors left their games early and now face uncertain timelines. While some situations appear relatively minor with the possibility of quick returns, others carry far more serious long-term implications. As always, context matters, and projecting availability in the coming weeks will be critical for setting lineups and planning roster moves.
Key: Position Player, Team | Injury | Projected Return to Play
WR Malik Nabers, New York Giants | Knee | Likely Season-Ending
During the Giants' win over the Chargers on Sunday, rookie WR Malik Nabers suffered a non-contact knee injury. Nabers' knee appeared to buckle inward, a mechanism that typically suggests an ACL tear. Nabers' knee injury resulted in him being carted to the locker room.
#Giants WR Malik Nabers is believed to have torn his ACL, per me and @TomPelissero. A crushing blow. pic.twitter.com/yF4tTnez3l
— Ian Rapoport (@RapSheet) September 28, 2025
Shortly after the game, NFL Network's Ian Rapoport reported that the Giants fear an ACL tear for their franchise wideout. While we are still awaiting official confirmation, the early signs point to a season-ending injury for Nabers.