Every week, the first step of your DFS homework should be to examine the opening Vegas odds on all the NFL games for that week. Through some fairly simple algebra, it is easy to derive a spreadsheet that predicts team totals for every game, thereby allowing you to develop a rudimentary gamescript to help narrow down your decisions for the week. Once the appealing (and unappealing) games have been highlighted, it becomes easier to focus upon those games to help build your core of players for that week; the caveat, however, is that the NFL is a dynamic league and anything is subject to change from Tuesday to Sunday...so keep that in mind as the week progresses and always monitor player injuries, weather conditions, and potential roster moves. Let's take a look.
[Blue font indicates games *not* on the DFS main slate.]
Updated Sunday, October 25nd @ 7 AM (EST)
| Team | Opponent | Odds | Game Total | Team Total | Passing | Running | Team Defense |
| Green Bay | Houston | -3.5 | 57 | 30.25 | ««« | ««« | |
| Seattle | Arizona | -3.5 | 55 | 29.25 | «« | «« | |
| Atlanta | Detroit | -2 | 55 | 28.5 | «« | «« | |
| Tampa Bay | Las Vegas | -5 | 52 | 28.5 | «« | «« | |
| New Orleans | Carolina | -6.5 | 50 | 28.25 | «« | ««« | |
| LA Chargers | Jacksonville | -7.5 | 49 | 28.25 | «« | ««« | |
| Buffalo | NY Jets | -10 | 46 | 28 | «« | ««« | « |
| Cleveland | Cincinnati | -3 | 50.5 | 26.75 | « | « | |
| Houston | Green Bay | 3.5 | 57 | 26.75 | « | « | |
| Detroit | Atlanta | 2 | 55 | 26.5 | « | « | |
| Tennessee | Pittsburgh | -1.5 | 51 | 26.25 | « | « | |
| Arizona | Seattle | 3.5 | 55 | 25.75 | |||
| Kansas City | Denver | -7 | 44 | 25.5 | « | ||
| LA Rams | Chicago | -6 | 45 | 25.5 | « | ||
| Pittsburgh | Tennessee | 1.5 | 51 | 24.75 | |||
| Philadelphia | NY Giants | -4.5 | 44.5 | 24.5 | |||
| Cincinnati | Cleveland | 3 | 50.5 | 23.75 | |||
| New England | San Francisco | -3 | 44.5 | 23.75 | |||
| Las Vegas | Tampa Bay | 5 | 52 | 23.5 | |||
| Washington | Dallas | -1 | 45 | 23 | Photos provided by Imagn Images
Tags:
Daily FF
DraftKings
FanDuel
Davante Adams
Josh Allen
Keenan Allen
Cole Beasley
Odell Beckham Jr
Le'Veon Bell
Tom Brady
John Brown
Chris Carson
Chase Claypool
Randall Cobb
James Conner
Brandin Cooks
Jared Cook
Stefon Diggs
Kenyan Drake
Eric Ebron
Clyde Edwards-Helaire
Mike Evans
Darren Fells
Will Fuller V
Chris Godwin
Kenny Golladay
Rob Gronkowski
Hunter Henry
Justin Herbert
Tyreek Hill
T.J. Hockenson
Austin Hooper
Kareem Hunt
Hayden Hurst
Justin Jackson
David Johnson
Aaron Jones
Julio Jones
Marvin Jones Jr
Ronald Jones II
Alvin Kamara
Travis Kelce
Joshua Kelley
Christian Kirk
Jarvis Landry
Tyler Lockett
Patrick Mahomes II
Baker Mayfield
DK Metcalf
Kyler Murray
Latavius Murray
Adrian Peterson
Calvin Ridley
Demarcus Robinson
Aaron Rodgers
Ben Roethlisberger
Matt Ryan
Emmanuel Sanders
Devin Singletary
JuJu Smith-Schuster
Matthew Stafford
D'Andre Swift
Michael Thomas
Robert Tonyan Jr
Marquez Valdes-Scantling
James Washington
Deshaun Watson
Mike Williams
Russell Wilson
Share This ArticleMore by John LeeDraftKings Thursday Showdown: Week 3
John Lee
Our John Lee with DraftKings Thursday Showdown Analysis: Dolphins vs. Bills
09/17/25
Read More
Vegas Value Chart: Week 3
John Lee
Examining Vegas NFL odds to pinpoint weekly DFS targets
09/15/25
Read More
DraftKings Thursday Showdown: Week 2
John Lee
Our John Lee with DraftKings Thursday Showdown Analysis: Commanders vs. Packers
09/11/25
Read More
Vegas Value Chart: Week 2
John Lee
Examining Vegas NFL odds to pinpoint weekly DFS targets
09/09/25
Read More
DraftKings Thursday Showdown: Week 1
John Lee
Our John Lee with DraftKings Thursday Showdown Analysis: Cowboys vs. Eagles
09/04/25
Read More
Vegas Value Chart: Week 1
John Lee
Examining Vegas NFL odds to pinpoint weekly DFS targets
09/03/25
Read More
|