Tight End
Logan Thomas, Washington (vs NY Giants)
Thomas was actually second on the team in receiving yards in the first matchup with the Giants, outgaining Curtis Samuel and Jahan Dotson. Sam Howell only completed 22 of 42 pass attempts and threw no touchdowns and one interception in a rough first outing against New York. Howell should be safe with the ball, which could include throwing more in the middle of the field to his biggest target.
Luke Musgrave, Green Bay (vs LA Chargers)
In addition to a wide receiver score or two, the Chargers are likely to give up numbers to the tight end position. Lions tight ends combined for 6-63-1 last week, Tyler Conklin posted a 6-66 line the week before that, Cole Kmet 10-79 the week before that, and Travis Kelce 12-179-1 the week before that. Musgrave has averaged 23 yards per reception with a score over the last two weeks, so he's a big play threat.
Donald Parham Jr, LA Chargers (at Green Bay)
Parham returned to practice on Thursday, so he should be good to go on Sunday at Lambeau against the Packers, who have been nursing a few injuries at linebacker at safety. Gerald Everett still isn't practicing, so Parham should dominate tight end targets and could be a prominent option in the red zone.
Quarterback
Matthew Stafford, LA Rams (vs Seattle)
Stafford is back from an injured thumb on his throwing hand that cost him one game before the bye, and just in time to face a Seahawks defense that he hung 334 passing yards on in Week 1. Seattle didn't have #5 overall pick Devon Witherspoon, but the Rams didn't have Cooper Kupp. The running backs scored all three touchdowns in Week 1, but if the Rams offense can find the end zone this week, it's more likely to be Stafford with the team down to a fourth and fifth-string committee backfield.
Jordan Love, Green Bay (vs LA Chargers)
Love hasn't been a fantasy star this year, but this week, he's facing a Chargers defense that has allowed at least 232 passing yards to every quarterback they have faced this season. That includes Tyson Bagent, Aidan O'Connell, Zach Wilson, and Ryan Tannehill. Four quarterbacks have scored as runners to add even more appeal to Love's outlook this week.
Dorian Thompson-Robinson, Cleveland (vs Pittsburgh)
Thompson-Robinson says he "knows what to expect" now and that the difference between this week and his first start back in Week 4 will be "night and day." We know he has a lot of ability as a runner, and the Steelers pass defense can be exploited if pressure doesn't get home. Thompson-Robinson is only a desperation play, including in 2QB/Superflex leagues, but he's one that at least comes with a chance to hit.
Aidan O'Connell, Las Vegas (at Miami)
O'Connell, like Thompson-Robinson, is a desperation play this week, but there's a path to value for him with the Dolphins possibly rendering most of the second half as garbage time if their offense can jump out to a big lead in the first half. Mike McDaniel has had two weeks to make adjustments to the offense, Jaylen Waddle will be healthier, and De'Von Achane should be back to add a big-play element to the running game. O'Connell should get a lot of pass attempts in the effort to keep up with the Dolphins.