Week 2 is coming your way, but before you rest your head on that nice, soft pillow and close your eyes, make sure your fantasy lineups are ready for Sunday.
Here are the marquee injuries worth tracking this week, along with the latest news and updates from Saturday.
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WR Ladd McConkey, LA Chargers | 4:05 EST Kickoff
Ladd McConkey returned to a limited practice Friday after sitting Wednesday and Thursday with a rib injury, making him a true game-time decision. Even if he's active, the concern isn't just whether he plays but whether pain or a limited role impacts his fantasy production. Historically, most wide receivers with rib injuries miss at least one game, and I'm uncomfortable trusting McConkey in Week 2 if I have a comparable healthy alternative or play in a chopped/guillotine league where a 0 could sink you.
TE Brock Bowers, Las Vegas | 4:05 EST Kickoff
Brock Bowers returned to practice Friday but remains doubtful as he works his way back from a meniscus procedure on the same knee that bothered him last season. His return to practice is encouraging, but he is still expected to sit in Week 2. Ideally, Bowers gets a full week of practice before returning, with Week 4 or beyond still looking like the safer timeline.
WR Zay Flowers, Baltimore | 1:00 EST Kickoff
Zay Flowers returned to practice Friday in a limited capacity. After being listed as doubtful for Week 2, the Ravens officially ruled him as out on Saturday. However, the limited practice is an encouraging development for Week 3 and if he continues progressing next week, a speeey return is possible. Flowers has a history of coming back sooner than the expected injury-specific timeline.
WR Nico Collins, Houston | 1:00 EST Kickoff
Nico Collins is out for Week 2 after suffering a new hamstring strain during Wednesday's practice. In-season hamstring strains typically cost NFL wide receivers around two weeks, and Collins has a history of soft-tissue injuries, including a five-week absence with a hamstring strain in 2024. Week 3 could be in jeopardy as well, so fantasy managers should prepare for the possibility of a multi-week absence.
WR Puka Nacua, LA Rams | 8:15 EST Kickoff - MONDAY
Puka Nacua did not practice Saturday, leaving him officially questionable for Monday night with a groin injury. Despite this concerning trend, there is reason for optimism: Nacua has played every time he's been listed as questionable from 2023-2025, including two instances when he didn't practice during the final practice of the week. For a player of Nacua's caliber, I'm willing to roll the dice and keep him in my lineup, but make no mistake in doing so, you’re rolling the dice based the practice reports this week. Ideally you would have a Monday-night pivot available should Nacua sit.
Our Bob Harris had this thought when making contingencies. Your first move is to put Nacua in the flex. Check your league's waiver wire for any viable Giants or Rams skill players who are likely to have a role. The list includes Giants WR Malachi Fields, who offers a WR-for-WR pivot without depending on another injured Ram. Fields' teammate Darnell Mooney is another possibility. Since the Rams will likely also be without Jordan Whittington (doubtful, quad), Los Angeles wideouts Konata Mumpfield and Tutu Atwell are viable.
Other potential flex options: Giants RB Devin Singletary; TEs Terrance Ferguson and Colby Parkinson are also deep fallback plans.
For the full Week 2 injury report, including the latest updates Sunday morning, historical injury data, and fantasy recommendations, check out the complete breakdown at Footballguys."
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