Week 5 Injuries, News, and Notes

Matchup previews for this week's NFL games, with all of the pertinent fantasy football news and notes.

Dave Kluge's Week 5 Injuries, News, and Notes Dave Kluge Published 10/03/2025

By Thursday afternoon, injury reports have usually told us most of the story. The final practice reports add the last details, but the week’s trends often give us a clear preview of what’s ahead in the coming weekend. Every Friday morning, Jeff Bell and Dave Kluge break down each matchup, highlighting the key injuries, depth chart shifts, and usage changes that matter for fantasy football. You can listen to the full podcast below for deeper analysis, or scroll through the matchup notes and bullet points for a quicker catch-up.

© Kirby Lee-Imagn Images, fantasy football, week 5 injuries, footballguys,

Bye Weeks

Atlanta Falcons, Chicago Bears, Green Bay Packers, Pittsburgh Steelers

Thursday Night Football - Thursday, 8:15 pm ET

San Francisco 49ers (4-1) @ Los Angeles Rams (3-2)

  • 49ers beat Rams 23-20

Sunday International Game - Sunday, 9:30 am ET

Minnesota Vikings (2-2) vs Cleveland Browns (1-3)

Sunday Early Games - Sunday, 1:00 pm ET

Houston Texans (1-3) @ Baltimore Ravens (1-3)

Miami Dolphins (1-3) @ Carolina Panthers (1-3)

Las Vegas Raiders (1-3) @ Indianapolis Colts (3-1)

New York Giants (1-3) @ New Orleans Saints (0-4)

Dallas Cowboys (1-2-1) @ New York Jets (0-4)

Denver Broncos (2-2) @ Philadelphia Eagles (4-0)

Sunday Afternoon Games - Sunday, 4:05 - 4:25 pm ET

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