Week 12 Injuries, News, and Notes

Week 12 matchup previews compiled by Dave Kluge with all of the news and notes pertinent to this week of fantasy football.

Dave Kluge's Week 12 Injuries, News, and Notes Dave Kluge Published 11/21/2025

By Thursday afternoon, injury reports have usually told us most of the story. The final practice reports add the last details, but the week's trends often give us a clear preview of what's ahead in the coming weekend. Every Friday morning, Jeff Bell and Dave Kluge break down each matchup, highlighting the key injuries, depth chart shifts, and usage changes that matter for fantasy football. You can listen to the full podcast below for deeper analysis, or scroll through the matchup notes and bullet points for a quicker catch-up.

© Thomas Shea-Imagn Images, week 12 injuries, fantasy football, footballguys

Bye Weeks

Denver Broncos, Los Angeles Chargers, Miami Dolphins, and Washington Commanders

Thursday Night Football - Thursday, 8:15 pm ET

Buffalo Bills (7-4) @ Houston Texans (6-5)

Sunday Early Games - Sunday, 1:00 pm ET

New York Jets (2-8) @ Baltimore Ravens (5-5)

Pittsburgh Steelers (6-4) @ Chicago Bears (7-3)

New England Patriots (9-2) @ Cincinnati Bengals (3-7)

New York Giants (2-9) @ Detroit Lions (6-4)

Minnesota Vikings (4-6) @ Green Bay Packers (6-3-1)

Indianapolis Colts (8-2) @ Kansas City Chiefs (5-5)

Seattle Seahawks  (7-3) @ Tennessee Titans (1-9)

Sunday Afternoon Games - Sunday, 4:05 - 4:25 pm ET

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