Week 16 Injuries, News, and Notes

Week 16 matchup previews compiled by Dave Kluge with all of the news and notes pertinent to this week of fantasy football.

Dave Kluge's Week 16 Injuries, News, and Notes Dave Kluge Published 12/19/2025

By Thursday afternoon, injury reports have usually told us most of the story. The final practice reports add the last details, but the week's trends often give us a clear preview of what's ahead in the coming weekend. Every Friday morning, Jeff Bell and Dave Kluge break down each matchup, highlighting the key injuries, depth chart shifts, and usage changes that matter for fantasy football. You can listen to the full podcast below for deeper analysis, or scroll through the matchup notes and bullet points for a quicker catch-up.

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Bye Weeks

None

Thursday Night Football - Thursday, 8:20 pm ET

Los Angeles Rams (11-4) @ Seattle Seahawks (12-3)

  • Seahawks beat Rams 38-37

Saturday Games - Sunday, 5:00 pm - 7:20 pm ET

Philadelphia Eagles (9-5) @ Washington Commanders (4-10)

Green Bay Packers (9-4-1) @ Chicago Bears (10-4)

Sunday Early Games - Sunday, 1:00 pm ET

Buffalo Bills (10-4) @ Cleveland Browns (3-11)

Los Angeles Chargers (10-4) @ Dallas Cowboys (6-7-1)

New York Jets (3-11) @ New Orleans Saints (4-10)

Tampa Bay Buccaneers (7-7) @ Carolina Panthers (7-7)

Minnesota Vikings (6-8) @ New York Giants (2-12)

  • Jalen Nailor (back) LP
  • All fantasy-relevant Giants are healthy

Kansas City Chiefs (6-8) @ Tennessee Titans (2-12)

Cincinnati Bengals (4-10) @ Miami Dolphins (6-8)

Sunday Afternoon Games - Sunday, 4:05 - 4:25 pm ET

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